In Figurines silico trials recently emerged as a disruptive technology, which may reduce the costs related to the development and marketing approval of novel medical technologies, as well as shortening their time-to-market.In these trials, virtual patients are recruited from a large database and their response to the therapy, such as the implantati
Cortical GABAergic interneurons in rodents originate in three subcortical regions: the medial ganglionic eminence (MGE), the lateral/caudal ganglionic eminence (LGE/CGE) and the preoptic area (POA).Each of these neuroepithelial precursor domains contributes different interneuron subtypes to the cortex.nNOS-expressing neurons represent a heterogenou
Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research.However, tissue availability, generation, and cultivation time represent important challenges for their usage.Therefore, the present study evaluated the efficacy of Outdoor Co